Carl R. Illig,Shelley K. Ballentine,Jinsheng Chen,Sanath K. Meegalla,M. Jonathan Rudolph,Mark J. Wall,Kenneth J. Wilson,Renee Louise Desjarlais,Carl M. Manthey,Christopher J. Molloy
申请号:
US14563126
公开号:
US09526731B2
申请日:
2014.12.08
申请国别(地区):
US
年份:
2016
代理人:
摘要:
A method of reducing or inhibiting kinase activity of C-KIT in a cell or a subject, and the use of such compounds for preventing or treating in a subject a cell proliferative disorder and/or disorders related to C-KIT using a compound of the present invention:or a solvate, hydrate, tautomer or pharmaceutically acceptable salt thereof.The present invention is further directed to methods for treating conditions such as cancers and other cell proliferative disorders.