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Process for Exploiting Synthetic Lethality Based on OverExpression of MYC Oncogene
专利权人:
Dun Yang
发明人:
Dun Yang,Jing Zhang,Shenqiu Zhang
申请号:
US15996697
公开号:
US20180346995A1
申请日:
2018.06.04
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention generally relates to inhibitor compounds and their use to selectively kill a class of cancer cells. Methods and means related to the treatment of cancers which overexpress the MYC family of oncogenes using Rho-associated protein kinase inhibitors, such as dimethylfasudil, which have shown to elicit cellular apoptosis, are provided herein.
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