Novel inhibitors for ERG oncogene positive cancers

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专利权人:

Inc.;The Henry M. Jackson Foundation for the Advancement of Military Medicine

发明人:

Dalgard, Clifton,Mohamed, Ahmed,Srivastava, Meera,Srivastava, Shiv

申请号：

AU2015229379

公开号：

AU2015229379B2

申请日:

2015.03.12

申请国别(地区):

AU

年份:

2018

代理人:

摘要：

Alterations to the ERG gene are some of the most prominent genomic changes associated with many cancers including prostate cancer. Such cancer specific alterations result in the overexpression of wild type ERG protein or an altered ERG protein. The present invention provides selective inhibitors of wild type or an altered ERG protein expression. The ERG inhibitors of the invention, therefore, are therapeutic agents for treating ERG positive cancers.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/