The Henry M. Jackson Foundation for the Advancement of Military Medicine; Inc.
发明人:
申请号：
EP15761120.3
公开号：
EP3116954A4
申请日:
2015.03.12
申请国别(地区):
EP
年份:
2017
代理人:
摘要：
Alterations to the ERG gene are some of the most prominent genomic changes associated with many cancers including prostate cancer. Such cancer specific alterations result in the overexpression of wild type ERG protein or an altered ERG protein. The present invention provides selective inhibitors of wild type or an altered ERG protein expression. The ERG inhibitors of the invention, therefore, are therapeutic agents for treating ERG positive cancers.
