NESBIT MARK,CAMERON BÉATRICE,BLANCHE FRANCIS,SORDELLO SYLVIE,NICOLAZZI CÉLINE,TROMBE MARC
申请号:
MYPI 20092137
公开号:
MY145914A
申请日:
2007.11.28
申请国别(地区):
MY
年份:
2012
代理人:
摘要:
THE INVENTION RELATES TO MODIFIED SOLUBLE FGF RECEPTOR FC FUSIONS COMPRISING A FUSION OF A SOLUBLE FRAGMENT OR DOMAIN OF THE FGF RECEPTOR PART (TARGETING OR BINDING MOIETY) WITH AN FC REGION OF AN IMMUNOGLOBULIN PART (EFFECTOR FUNCTION MOIETY), HAVING IMPROVED BIOLOGICAL ACTIVITY INCLUDING ADCC/CDC ACTIVITIES, COMPOSITIONS CONTAINING THEM, AND IO METHOD OF PRODUCING SUCH MODIFIED SOLUBLE FGF RECEPTOR FC FUSION MOLECULES.