Sordello, Sylvie,Nesbit, Mark,Cameron, Beatrice,Trombe, Marc,Nicolazzi, Celine,Blanche, Francis
申请号:
AU2007326985
公开号:
AU2007326985B2
申请日:
2007.11.28
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
The invention relates to modified soluble FGF receptor Fc fusions comprising a fusion of a soluble fragment or domain of the FGF receptor part (targeting or binding moiety) with an Fc region of an immunoglobulin part (effector function moiety), having improved biological activity including ADCC/CDC activities, compositions containing them, and method of producing such modified soluble FGF receptor Fc fusion molecules.