Francis BLANCHE,Béatrice CAMERON,Sylvie SORDELLO,Céline NICOLAZZI,Marc TROMBE,Mark NESBIT
申请号:
US13931184
公开号:
US20140030265A1
申请日:
2013.06.28
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The invention relates to modified soluble FGF receptor Fc fusions comprising a fusion of a soluble fragment or domain of the FGF receptor part (targeting or binding moiety) with an Fc region of an immunoglobulin part (effector function moiety), having improved biological activity including ADCC/CDC activities, compositions containing them, and method of producing such modified soluble FGF receptor Fc fusion molecules.