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INHIBITEURS POLYHETEROARYLE DE L'HISTONE DESACETYLASE ET LEUR UTILISATION EN THERAPIE
专利权人:
KARUS THERAPEUTICS LTD
发明人:
SHUTTLEWORTH, STEPHEN JOSEPH,CECIL, ALEXANDER RICHARD LIAM,MACCORMICK, SOMHAIRLE,NODES, WILLIAM JOHN,TOMASSI, CYRILLE DAVY,SILVA, FRANCK ALEXANDRE
申请号:
CA2966070
公开号:
CA2966070A1
申请日:
2015.10.29
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The present invention is a compound having the following formula: or a pharmaceutically acceptable salt thereof, wherein e.g. L and Y are each independently an optionally substituted 6-membered nitrogen-containing heteroaryl; M is an optionally substituted 5- to 10-membered heteroaryl; W is a zinc-binding group; each R2 is independently hydrogen or C1-C6 alkyl; and R3 is an aryl or heteroaryl. The compounds are useful as histone deacetylase (HDAC) inhibitors.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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