William Don HARRIMAN;Crystal Bioscience Inc.;Philip A. LEIGHTON;Robert ETCHES
发明人:
William Don HARRIMAN,Robert ETCHES,Philip A. LEIGHTON
申请号:
IL25762318
公开号:
IL257623D0
申请日:
2018.02.20
申请国别(地区):
IL
年份:
2018
代理人:
摘要:
This disclosure provides, among other things, a transgenic animal and a method of using the same to make antibodies that have a common light chain. In certain embodiments, the transgenic animal may comprising a genome comprising a common light chain transgene, wherein the common light chain transgene comprises a non-immunoglobulin light-chain promoter and a common light-chain coding sequence. In certain embodiments, the common light chain is constitutively expressed.