HARRIMAN WILLIAM DON,ETCHES ROBERT,LEIGHTON PHILIP A
申请号:
IN201817007668
公开号:
IN201817007668A
申请日:
2018.03.01
申请国别(地区):
IN
年份:
2018
代理人:
摘要:
This disclosure provides among other things a transgenic animal and a method of using the same to make antibodies that have a common light chain. In certain embodiments the transgenic animal may comprising a genome comprising a common light chain transgene wherein the common light chain transgene comprises a non immunoglobulin light chain promoter and a common light chain coding sequence. In certain embodiments the common light chain is constitutively expressed.