William Don Harriman,Robert Etches,Philip A. Leighton
申请号：
US15753938
公开号：
US20180249687A1
申请日:
2016.08.24
申请国别(地区):
US
年份:
2018
代理人:
摘要：
This disclosure provides, among other things, a transgenic animal and a method of using the same to make antibodies that have a common light chain. In certain embodiments, the transgenic animal may comprising a genome comprising a common light chain transgene, wherein the common light chain transgene comprises a non-immunoglobulin light-chain promoter and a common light-chain coding sequence. In certain embodiments, the common light chain is constitutively expressed.
