Carl R. Illig,Shelley K. Balltentine,Jinsheng Chen,Sanath K. Meegalla,M. Jonathan Rudolph,Mark J. Wall,Kenneth J. Wilson,Renee L. DesJarlais,Carl L. Manthey,Christopher J. Molloy
申请号:
US11737517
公开号:
US08697716B2
申请日:
2007.04.19
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A method of reducing or inhibiting kinase activity of C-KIT in a cell or a subject, and the use of such compounds for preventing or treating in a subject a cell proliferative disorder and/or disorders related to C-KIT using a compound of the present invention:or a solvate, hydrate, tautomer or pharmaceutically acceptable salt thereof.The present invention is further directed to methods for treating conditions such as cancers and other cell proliferative disorders.