Macdonald, Lynn,Gurer, Cagan,Hosiawa, Karolina A.,Stevens, Sean,Murphy, Andrew J.
申请号：
AU2015238803
公开号：
AU2015238803A1
申请日:
2015.10.07
申请国别(地区):
AU
年份:
2015
代理人:
摘要：
#$%^&*AU2015238803A120151029.pdf#####ABSTRACT Non-human animals, tissues, cells, and genetic material are provided that comprise a modification of an endogenous non-human heavy chain immunoglobulin sequence and that comprise an ADAM6 activity functional in a mouse, wherein the non-human animals express a human immunoglobulin heavy chain variable domain and a cognate human immunoglobulin X light chain variable domain.
