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Thiophenediamine derivative having urea structure
专利权人:
Minoru Yamamoto;Yusuke Yamazaki;Hisashi Tajima;Noriko Mishina;Shinji Yoneda;Hiroyuki Mogi;Katsuhiko Watanabe;Junko Fujikawa
发明人:
Hiroyuki Mogi,Hisashi Tajima,Noriko Mishina,Yusuke Yamazaki,Shinji Yoneda,Katsuhiko Watanabe,Junko Fujikawa,Minoru Yamamoto
申请号:
US13448674
公开号:
US08288380B2
申请日:
2012.04.17
申请国别(地区):
US
年份:
2012
代理人:
摘要:
A compound of formula (1):wherein R1 and R2 represent hydrogen, lower alkyl, lower alkenyl, lower alkynyl orR3 represents hydroxyl, lower alkoxy, lower cycloalkyloxy, aryloxy, carboxy, lower alkoxycarbonyl, or NRaRb of the formulaR4 and R5 represent halogen, lower alkyl, hydroxyl, or lower alkoxy; R6 represents halogen, lower alkyl, aryl, heterocyclic, hydroxy, lower alkoxy, mercapto, lower alkylthio, lower alkylcarbonyl, amino, nitro or cyano; R7 represents lower alkyl, hydroxyl or lower alkoxy; Ra and Rb represent hydrogen or lower alkyl; ring A represents a cyclic hydrocarbon or a heterocyclic ring; ring B represents a heterocyclic ring; X represents lower alkylene; Z represents a single bond or lower alkylene; Y represents lower alkylene and W1—W2 represents CH—CH, or Y represents a single bond and W1—W2 represents N—CH, CH—N or CH—CH; and 1, m, n and o represent 0, 1, 2, or 3.
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