Jingwu Duan,T. G. Murali Dhar,David Marcoux,Qing Shi,Douglas G. Batt,Qingjie Liu,Robert J. Cherney,Lyndon A. M. Cornelius,Anurag S. Srivastava,Myra Beaudoin Bertrand,Carolyn A. Weigelt
申请号：
US15148209
公开号：
US09815859B2
申请日:
2016.05.06
申请国别(地区):
US
年份:
2017
代理人:
摘要：
There are described RORγ modulators of the formula (I),and formula (II)or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein all substituents are defined herein. Also provided are pharmaceutical compositions comprising the same. Such compounds and compositions are useful in methods for modulating RORγ activity in a cell and methods for treating a subject suffering from a disease or disorder in which the subject would therapeutically benefit from modulation of RORγ activity, for example, autoimmune and/or inflammatory disorders.
