MARCOUX, DAVID,BEAUDOIN BERTRAND, MYRA,DHAR, T.G. MURALI,YANG, MICHAEL G.,XIAO, ZILI,XIAO, HAI-YUN,ZHU, YEHENG,WEIGELT, CAROLYN A.,BATT, DOUGLAS G.
申请号:
CA3042877
公开号:
CA3042877A1
申请日:
2017.11.08
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
There are described ROR? Gamma modulators of the formula (I), (I) or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein all substituents are defined herein. Also provided are pharmaceutical compositions comprising the same. Such compounds and compositions are useful in methods for modulating ROR? activity in a cell and methods for treating a subject suffering from a disease or disorder in which the subject would therapeutically benefit from modulation of ROR? activity, for example, autoimmune and/or inflammatory disorders.