Duan, Jingwu,Dhar, T.G. Murali,Marcoux, David,Shi, Qing,Batt, Douglas G.,Liu, Qingjie,Cherney, Robert J.,Cornelius, Lyndon A.M.,Srivastava, Anurag S.,Beaudoin Bertrand, Myra,Weigelt, Carolyn A.
申请号:
AU2016258087
公开号:
AU2016258087A1
申请日:
2016.05.06
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
There are described RORϒ modulators of the formula (I), and formula (II) or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein all substituents are defined herein. Also provided are pharmaceutical compositions comprising the same. Such compounds and compositions are useful in methods for modulating RORϒ activity in a cell and methods for treating a subject suffering from a disease or disorder in which the subject would therapeutically benefit from modulation of RORϒ activity, for example, autoimmune and/or inflammatory disorders.