8 - CARBAMOYL - 2 - (2,3- DI SUBSTITUTED PYRID - 6 - YL) -1,2,3,4 -TETRAHYDROISOQUINOLINE DERIVATIVES AS APOPTOSIS - INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES
WANG, Le,DOHERTY, George,WANG, Xilu,TAO, Zhi-Fu,BRUNKO, Milan,KUNZER, Aaron R,WENDT, Michael D,SONG, Xiaohong,FREY, Robin,HANSEN, Todd M,SULLIVAN, Gerard M,JUDD, Andrew,SOUERS, Andrew
申请号：
PH12015501498
公开号：
PH12015501498B1
申请日:
2015.06.30
申请国别(地区):
PH
年份:
2015
代理人:
摘要：
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-xL proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-xL protein.
