SINGAPORE HEALTH SERVICES PTE LTD;NANYANG TECHNOLOGICAL UNIVERSITY
发明人:
VADAKKE MATHAM, Murukeshan,VENGALATHUNADAKAL KUTTINARAYANAN, Shinoj,HONG, Xun Jie Jesmond,MANI, Baskaran,AUNG, Tin
申请号：
SGSG2016/050089
公开号：
WO2016/137396A1
申请日:
2016.02.24
申请国别(地区):
SG
年份:
2016
代理人:
摘要：
According to various embodiments, there is provided an imaging device including a Bessel beam generator configured to provide a Bessel beam； a scanning mirror configured to scan the Bessel beam across a two-dimensional plane； a scan lens configured to receive the Bessel beam from the scanning mirror, a centre of the scan lens being at least substantially a focal length of the scan lens away from the scanning mirror； an illumination tube lens configured to receive the Bessel beam from the scan lens, a centre of the illumination tube lens being at least substantially a sum of the focal length of the scan lens and a focal length of the illumination tube lens away from the centre of the scan lens； an illumination objective lens positioned in direct line-of-sight to a specimen, the illumination objective lens configured to receive the Bessel beam from the illumination tube lens and further configured to illuminate the specimen with the Bessel beam, wherein a centre of the illumination objective lens is at least substantially the focal length of the illumination tube lens away from the centre of the illumination tube lens； and a detection optics arrangement configured to receive a reflected beam (emitted fluorescence beam) from the specimen.Selon divers modes de réalisation, l'invention concerne un dispositif d'imagerie comprenant un générateur de faisceau de Bessel configuré pour fournir un faisceau de Bessel ； un miroir de balayage configuré pour faire balayer le faisceau de Bessel sur un plan à deux dimensions ； une lentille de balayage configurée pour recevoir le faisceau de Bessel provenant du miroir de balayage, un centre de la lentille de balayage étant au moins sensiblement distant d'une longueur focale de la lentille de balayage par rapport au miroir de balayage ； une lentille de tube d'éclairage configurée pour recevoir le faisceau de Bessel provenant de la lentille de balayage, un centre de la lentille de tube d'éclairage étant au moins sensiblement distant d'u
