More particularly, the present invention relates to a composition for external application for skin containing extracts of Machilus thunbergii. More particularly, the present invention relates to a composition for external application for skin, which has excellent activity of inhibiting wound healing, skin regeneration, cell activity and inflammatory mediator production, The present invention relates to a composition for external application for skin containing as an active ingredient.NF-κB, IL-1β, TNF-α, PGE2, and NF-κB were found to be responsible for wound healing, skin regeneration,본 발명은 토후박(Machilus thunbergii)의 추출물을 함유하는 피부 외용제 조성물에 관한 것으로, 보다 상세하게는 상처 치유, 피부 재생, 세포 활성 및 염증 매개 인자의 생성을 저해하는 활성이 뛰어난 토후박의 추출물을 유효성분으로 함유하는 피부 외용제 조성물에 관한 것이다.
