Lawrence Livermore National Security, LLC;The Regents of the University of California
发明人:
Balhorn, Rodney L.,Denardo, Sally J.,Denardo, Gerald L.
申请号：
AU2009239491
公开号：
AU2009239491B2
申请日:
2009.04.21
申请国别(地区):
AU
年份:
2014
代理人:
摘要：
This invention provides novel polydentate selective high affinity ligands (SHALs) that can be used in a variety of applications in a manner analogous to the use of antibodies. SHALs typically comprise a multiplicity of ligands that each bind different region son the target molecule. The ligands are joined directly or through a linker thereby forming a polydentate moiety that typically binds the target molecule with high selectivity and avidity.
