SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH

• 收藏
• 分享

专利权人:

THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

发明人:

DENARDO, SALLY, J.,DENARDO, GERALD, L.,BALHORN, RODNEY, L.

申请号：

EP09734156

公开号：

EP2268654A4

申请日:

2009.04.21

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

This invention provides novel polydentate selective high affinity ligands (SHALs) that can be used in a variety of applications in a manner analogous to the use of antibodies. SHALs typically comprise a multiplicity of ligands that each bind different region son the target molecule. The ligands are joined directly or through a linker thereby forming a polydentate moiety that typically binds the target molecule with high selectivity and avidity.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/