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Oligosaccharide conjugates and methods of use
专利权人:
THE SECRETARY OF STATE FOR ENVIRONMENT, FOOD AND RURAL AFFAIRS;THE GOVERNORS OF THE UNIVERSITY OF ALBERTA
发明人:
John McGiven,David Bundle,Laurence Howells,Julie Guiard,Vijaya Ganesh Narayanaswamy
申请号:
US14784662
公开号:
US09744245B2
申请日:
2014.04.16
申请国别(地区):
US
年份:
2017
代理人:
摘要:
There is provided a method of detecting in a sample the presence of an anti-M and/or anti-A and/or anti-C/Y antibody, the method comprising contacting the sample with a diagnostic conjugate provided according to the invention, comprising an oligosaccharide which comprises at least two units of 4,6-dideoxy-4-acylamido-α-pyranose and comprising at least one -(1-3)-link between adjacent 4,6-dideoxy-4-acylamido-α-pyranose units, in which the carbon at position 5 in the pyranose is linked to an R group, where R is independently selected from —CH2OH, —H or an alkyl group having at least one C atom, the oligosaccharide being covalently linked to a non-saccharide molecule or to a surface.
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