The invention relates to a tight and cryoresistant device for the injection of a solution, said device being designed to be associated with a needle for the subsequent injection of said solution and comprising an injection body (1), a stopper (21), and a piston head, characterised in that: the injection body (1) comprises a first proximal end closed in a tight manner by the piston head and a second distal end closed in a tight manner by the stopper (21)； and the stopper (21) is held on the injection body (1) by a fixing element and comprises a breakable portion allowing the arrangement of a needle, the stopper (21) being a separable stopper (21), the separation of a separable portion (211) releasing a means for fixing an injector comprising a needle. The materials forming the device are cryoresistant.
