A protective apparatus for a chemotherapy injection needle, includes a coring needle, a plastic film integrated with a hand-held film, and an injection vessel, wherein the coring needle is a through, hollow and metal needle having a needle head bent downwards to form an angle with a needle body which connects to the injection vessel at a rear end. The plastic film has two trapezoidal and protruding wings extending to two sides, and when the two protruding wings are folded to clamp the needle head, the protruding wings extending length is sufficient to wrap a tip part of the needle head, and positions where the protruding wings wrap the tip part are corresponding to concaved grooves of the needle head, so that the two protruding wings attach closely with each other. Also, the two protruding wings engage with each other by a locking device to secure the protruding wings.