BROWN, BRIAN S,KOENIG, JOHN R,GOMTSYAN, ARTHUR R,LEE, CHIH-HUNG
申请号：
NZ57170607
公开号：
NZ571706A
申请日:
2007.04.12
申请国别(地区):
NZ
年份:
2012
代理人:
摘要：
The disclosure relates to spiro-chroman compounds of formula (I), wherein the variables X1, X2, Y, R1a, R1, R2a, R2b, A1, A2, A3, and A4 are as defined in the specification. These compounds have vanilloid receptor subtype I (VR1) inhibiting activity and are suitable for use in treating pain, neuropathic pain, allodynia, pain associated with inflammation or an inflammatory disease, inflammatory hyperalgesia, bladder overactivity, and urinary incontinence.
