Robert G. Schmidt, Jr.;Steven P. Latshaw;Jerome F. Daanen;Arthur Gomtsyan;Tammie K. Jinkerson;John R. Koenig;Erol K. Bayburt;Brian S. Brown;Chih-Hung Lee
发明人:
Arthur Gomtsyan,Erol K. Bayburt,Robert G. Schmidt, Jr.,Chih-Hung Lee,Brian S. Brown,Tammie K. Jinkerson,John R. Koenig,Jerome F. Daanen,Steven P. Latshaw
申请号:
US12875839
公开号:
US08440691B2
申请日:
2010.09.03
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Compounds that are antagonists of the VR1 receptor, having formula (I)or a pharmaceutically acceptable salt, prodrug, or salt of a prodrug thereof, wherein A1, A2, A3, A4, R7, R8, R9, X, Y, Z, L, n, and m, are as defined herein, and are useful in disorders prevented or ameliorated by inhibiting the VR1 receptor.