Brian S. Brown;Chih-Hung Lee;Arthur R. Gomtsyan;John R. Koenig
发明人:
Brian S. Brown,John R. Koenig,Arthur R. Gomtsyan,Chih-Hung Lee
申请号：
US12474035
公开号：
US08598220B2
申请日:
2009.05.28
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention is directed to compounds of formula (I)wherein variables X1, X2, Y, R1a, R1b, R2a, R2b, A1, A2, A3, and A4 are as defined in the description, and methods of use to treat pain, neuropathic pain, allodynia, pain associated with inflammation or an inflammatory disease, inflammatory hyperalgesia, bladder overactivity, and urinary incontinence.
