DAVID URECH,ADRIAN AUF DER MAUR,ALCIDE BARBERIS,PETER LICHTLEN
申请号：
NZ70027507
公开号：
NZ700275A
申请日:
2007.07.10
申请国别(地区):
NZ
年份:
2016
代理人:
摘要：
A pharmaceutical composition formulated for local application to the skin comprising a soluble scFv antibody or a functional antibody fragment capable of crossing an epithelial layer in less than 4 hours wherein said scFv antibody or functional antibody fragment reveals a midpoint of transition in guanidinium hydrochloride 5 titration of at least 1.5M and wherein said scFv antibody or functional antibody fragment is capable of crossing said epithelial layer in the absence of a penetration enhancer.
