PROCÉDÉS PERMETTANT D'AMÉLIORER LE TRAITEMENT PAR BLOCAGE DU POINT DE CONTRÔLE IMMUNITAIRE EN MODULANT LE MICROBIOME

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专利权人:

Board of Regents; The University of Texas System

发明人:

WARGO, Jennifer,GOPALAKRISHNAN, Vancheswaran

申请号：

EP17857329

公开号：

EP3518946A4

申请日:

2017.09.27

申请国别(地区):

EP

年份:

2020

代理人:

摘要：

Provided herein are methods and compositions for the treatment of cancer by modulating the microbiome to enhance the efficacy of immune checkpoint blockade. The microbiome may be modulated by the administration of butyrate and/or butyrate-producing bacteria. Also provided herein are methods of determining a response to an immune checkpoint inhibitor by identifying if a subject has a favorable microbial profile.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/