THE BOARD OF REGENTS; THE UNIVERSITY OF TEXAS SYSTEM
发明人:
Jennifer WARGO,Vancheswaran GOPALAKRISHNAN
申请号：
US16337820
公开号：
US20200129569A1
申请日:
2017.09.27
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Provided herein are methods and compositions for the treatment of cancer by modulating the microbiome to enhance the efficacy of immune checkpoint blockade. The microbiome may be modulated by the administration of butyrate and/or butyrate-producing bacteria. Also provided herein are methods of determining a response to an immune checkpoint inhibitor by identifying if a subject has a favorable microbial profile.
