HEISER, Ryan,GARDAI, Shyra,TAFT, David,OGDEN, Carol Anne
申请号:
SG11202002697W
公开号:
SG11202002697WA
申请日:
2018.10.11
申请国别(地区):
SG
年份:
2020
代理人:
摘要:
The invention provides methods and compositions for modulating the immune response in a subject, such as decreasing the activity of CD30+ T regulatory cells and increasing the ratio of CD8+ T cells to CD30+ T regulatory cells, through administration of antibody drug- conjugates that bind to CD30. The invention also provides articles of manufacture or kits comprising said antibody drug-conjugates that bind to CD30 for modulating the immune response.