Ryan HEISER,Shyra GARDAI,David TAFT,Carol Anne OGDEN
申请号：
US16755091
公开号：
US20200239585A1
申请日:
2018.10.11
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The invention provides methods and compositions for modulating the immune response in a subject, such as decreasing the activity of CD30+ T regulatory cells and increasing the ratio of CD8+ T cells to CD30+ T regulatory cells, through administration of antibody drug-conjugates that bind to CD30. The invention also provides articles of manufacture or kits comprising said antibody drug-conjugates that bind to CD30 for modulating the immune response.
