GRUE-SORENSEN, GUNNAR,LIANG, XIFU,HOGBERG, THOMAS,MANSSON, KRISTOFFER,VEDSO, PER
申请号：
CA2822312
公开号：
CA2822312A1
申请日:
2011.12.22
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
The invention relates to compounds of general formula I, (I), wherein R is wherein R is aryl substituted by R3； or R is (C3-Ci3)-cycloalkyl, (C3-Ci3)- cycloalkenyl or (C7-Ci3)-cycloalkynyl optionally substituted by R4； and pharmaceutically acceptable salts, hydrates, or solvates thereof, for use -alone or in combination with one or more other pharmaceutically active compounds- in therapy, for preventing, treating or ameliorating diseases or conditions responsive to stimulation of neutrophil oxidative burst, responsive to stimulation of keratinocyte IL-8 release or responsive to induction of necrosis.
