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INGENOL-3-ACYLATES I
专利权人:
LEO LABORATORIES LIMITED
发明人:
GRUE-SORENSEN, GUNNAR,LIANG, XIFU,HOGBERG, THOMAS
申请号:
CA2822360
公开号:
CA2822360A1
申请日:
2011.12.22
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The invention relates to compounds of general formula (I) wherein R is (C1-C7)alkyl, (C2-C7)alkenyl or (C2-C7)alkynyl; wherein R is substituted with R1; and pharmaceutically acceptable salts, hydrates, or solvates thereof, for use -alone or in combination with one or more other pharmaceutically active compounds- in therapy, for preventing, treating or ameliorating diseases or conditions responsive to stimulation of neutrophil oxidative burst, responsive to stimulation of keratinocyte IL-8 release or responsive to induction of necrosis.
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