Grue-Sorensen, Gunnar,Liang, Xifu,Hogberg, Thomas,Mansson, Kristoffer,Vedso, Per,Vifian, Thomas
申请号:
AU2011348637
公开号:
AU2011348637B2
申请日:
2011.12.22
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
The invention relates to compounds of general formula I wherein R is heteroaryl optionally substituted by R7; or R is heterocycloalkyl or heterocycloalkenyl, optionally substituted by R8; or R is X wherein X is -NR11R12; and pharmaceutically acceptable salts, hydrates, or solvates thereof, for use -alone or in combination with one or more other pharmaceutically active compounds- in therapy, for preventing, treating or ameliorating diseases or conditions responsive to stimulation of neutrophil oxidative burst, responsive to stimulation of keratinocyte IL-8 release or responsive to induction of necrosis.