GRUE-SORENSEN, GUNNAR,LIANG, XIFU,HOGBERG, THOMAS,MANSSON, KRISTOFFER,VEDSO, PER,VIFIAN, THOMAS
申请号：
CA2822310
公开号：
CA2822310A1
申请日:
2011.12.22
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
The invention relates to compounds of general formula I wherein R is heteroaryl optionally substituted by R7； or R is heterocycloalkyl or heterocycloalkenyl, optionally substituted by R8； or R is X wherein X is -NR11R12； and pharmaceutically acceptable salts, hydrates, or solvates thereof, for use -alone or in combination with one or more other pharmaceutically active compounds- in therapy, for preventing, treating or ameliorating diseases or conditions responsive to stimulation of neutrophil oxidative burst, responsive to stimulation of keratinocyte IL-8 release or responsive to induction of necrosis.
