GRUE-SØRENSEN, GUNNAR,LIANG, XIFU,HÖGBERG, THOMAS,MÅNSSON, KRISTOFFER,VEDSØ, PER,VIFIAN, THOMAS
申请号:
SG2013046438
公开号:
SG191196A1
申请日:
2011.12.22
申请国别(地区):
SG
年份:
2013
代理人:
摘要:
The invention relates to compounds of general formula I wherein R is heteroaryl optionally substituted by R7; or R is heterocycloalkyl or heterocycloalkenyl, optionally substituted by R8; or R is X wherein X is -NR11R12; and pharmaceutically acceptable salts, hydrates, or solvates thereof, for use -alone or in combination with one or more other pharmaceutically active compounds- in therapy, for preventing, treating or ameliorating diseases or conditions responsive to stimulation of neutrophil oxidative burst, responsive to stimulation of keratinocyte IL-8 release or responsive to induction of necrosis.