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3-acyl-ingenols II
专利权人:
Leo Pharma A/S
发明人:
Grue-Sorensen, Gunnar,Liang, Xifu,Hogberg, Thomas,Mansson, Kristoffer,Vedso, Per
申请号:
AU2011348638
公开号:
AU2011348638A1
申请日:
2011.12.22
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
The invention relates to compounds of general formula I, (I), wherein R is wherein R is aryl substituted by R3; or R is (C3-Ci3)-cycloalkyl, (C3-Ci3)- cycloalkenyl or (C7-Ci3)-cycloalkynyl optionally substituted by R4; and pharmaceutically acceptable salts, hydrates, or solvates thereof, for use -alone or in combination with one or more other pharmaceutically active compounds- in therapy, for preventing, treating or ameliorating diseases or conditions responsive to stimulation of neutrophil oxidative burst, responsive to stimulation of keratinocyte IL-8 release or responsive to induction of necrosis.
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中国工程科技知识中心
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