Gunnar Grue-Sørensen;Thomas Högberg;Kristoffer Månsson;Per Vedsø;Xifu Liang
发明人:
Gunnar Grue-Sørensen,Xifu Liang,Thomas Högberg,Kristoffer Månsson,Per Vedsø
申请号：
US13997011
公开号：
US20130331446A1
申请日:
2011.12.22
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The invention relates to compounds of general formula I, (I), wherein R is wherein R is aryl substituted by R3； or R is (C3-Ci3)-cycloalkyl, (C3-Ci3)-cycloalkenyl or (C7-Ci3)-cycloalkynyl optionally substituted by R4； and pharmaceutically acceptable salts, hydrates, or solvates thereof, for use—alone or in combination with one or more other pharmaceutically active compounds—in therapy, for preventing, treating or ameliorating diseases or conditions responsive to stimulation of neutrophil oxidative burst, responsive to stimulation of keratinocyte IL-8 release or responsive to induction of necrosis.
