PAOLA CIAPETTI,FRANÇOISE LEBBLANC,MARC SCHNEIDER,SANDRINE ROPP,CHRISTOPHE MORICE,BRUNO GIETHLEN,CAMILLE G. WERMUTH,FLORENCE CHERY-MOZZICONACCI
申请号：
BRPI0906048
公开号：
BRPI0906048A2
申请日:
2009.02.26
申请国别(地区):
BR
年份:
2015
代理人:
摘要：
A subject of the invention is the compounds of formula (I): in which either R1 represents H, OH, NH2, &mdash；(CH2)m&mdash；NRaRb(m=0.1 or 2), Ra and Rb represent H, linear, branched or cyclic (C1-C6) alkyl, (C3-C6) cycloalkyl-(C3-C6)&mdash； alkyl, Rc, S(O)2Rc, C(O)Rc, S(O)2Rd or C(O)Rd； or Ra and Rb with N form an Rc radical； Rc represents a saturated, unsaturated or 5- or 6-members aromatic ring, containing 1 to 4 heteroatoms chosen from N, O and S, optionally substituted； Rd represents a linear, branched or cyclic (C1-C6) alkyl, optionally substituted by 1 to 4 halogens； or R1 represents Rc or CHReRc or CHReRd； Re represents H, OH, NH2, NH&mdash；(C1-C6)-alk or N-(C1-C6)-alk2, or NH&mdash；(C1-C7)-acyl or NHRc； R2 represents H, (CH2)m&mdash；NRaRb, Rc, CHReRc or CHReRd, and R&prime；2 represents H.
