CHRISTIAN VAN DEN BOS;CLAUDIA ROSENBAUM;BARBARA REINISCH;JUDITH SCHENK
发明人:
CHRISTIAN VAN DEN BOS,BARBARA REINISCH,JUDITH SCHENK,CLAUDIA ROSENBAUM
申请号：
US15688148
公开号：
US20180055888A1
申请日:
2017.08.28
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The invention encompasses compositions and method of treating a vascular disease such as peripheral artery disease, The methods involve—administering to a patient in need thereof, an effective amount of a composition comprising a population of cells such as mesenchymal stem cells (MSCs) and a non-muscle myosin 0 antagonist such as blebbistatin. Non-muscle myosin II antagonists are disclosed to surprisingly and dramatically accelerate MSC-triggered regeneration of damaged tissues arid unexpectedly and drastically reduce severe complications of stem cell treatment.
