CHRISTIAN VAN DEN BOS,BARBARA REINISCH,JUDITH SCHENK,CLAUDIA ROSENBAUM
申请号:
US16738495
公开号:
US20200147142A1
申请日:
2020.01.09
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The invention encompasses compositions and method of treating a vascular disease such as peripheral artery disease, The methods involve—;administering to a patient in need thereof, an effective amount of a composition comprising a population of cells such as mesenchymal stem cells (MSCs) and a non-muscle myosin 0 antagonist such as blebbistatin. Non-muscle myosin II antagonists are disclosed to surprisingly and dramatically accelerate MSC-triggered regeneration of damaged tissues arid unexpectedly and drastically reduce severe complications of stem cell treatment.