VAN DEN BOS, CHRISTIAN,REINISCH, BARBARA,SCHENK, JUDITH,ROSENBAUM, CLAUDIA
申请号：
CA2905650
公开号：
CA2905650A1
申请日:
2014.03.13
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
The invention encompasses compositions and method of treating a vascular disease such as peripheral artery disease, The methods involve- administering to a patient in need thereof, an effective amount of a composition comprising a population of cells such as mesenchymal stem cells (MSCs) and a non-muscle myosin 0 antagonist such as blebbistatin. Non-muscle myosin II antagonists are disclosed to surprisingly and dramatically accelerate MSC-triggered regeneration of damaged tissues arid unexpectedly and drastically reduce severe complications of stem cell treatment.
