MJALLI ADNAN M M,HARI ANITHA,GADDAM BAPU,GOHIMUKKULA DEVI REDDY,POLISETTI DHARMA RAO,EL ABDELLAOUI HASSAN,RAO MOHAN,ANDREWS ROBERT CARL,XIE RONGYUAN,REN TAN
申请号:
IN7497/DELNP/2011
公开号:
IN2011DN07497A
申请日:
2011.09.29
申请国别(地区):
IN
年份:
2013
代理人:
摘要:
The present invention is directed to substituted imidazo[1,2-a]pyridine derivatives, pharmaceutically acceptable salts thereof, and tautomers of such compounds or salts, that inhibit ß-site amyloid precursor protein-cleaving enzyme (BACE) and that may be useful in the treatment of diseases in which BACE is involved, such as Alzheimers disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which BACE is involved.