Guoxiang Huang;Robert C. Andrews;Jeff J. Zhu;Devi Reddy Gohimukkula;David R. Jones;Mohan Rao;Tan Ren;Adnan M. M. Mjalli
发明人:
Adnan M. M. Mjalli,David R. Jones,Devi Reddy Gohimukkula,Guoxiang Huang,Jeff J. Zhu,Mohan Rao,Robert C. Andrews,Tan Ren
申请号：
US12950718
公开号：
US08598353B2
申请日:
2010.11.19
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention is directed to benzazole compounds that inhibit β-site amyloid precursor protein-cleaving enzyme (BACE) and that may be useful in the treatment or prevention of diseases in which BACE is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which BACE is involved.
