Adnan M. M. Mjalli,David Robert Jones,Devi Reddy Gohimukkula,Guoxiang Huang,Jeff Jiqun Zhu,Mohan Rao,Robert Carl Andrews,Tan Ren
申请号:
US14064737
公开号:
US08946259B2
申请日:
2013.10.28
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention is directed to benzazole compounds that inhibit β-site amyloid precursor protein-cleaving enzyme (BACE) and that may be useful in the treatment or prevention of diseases in which BACE is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which BACE is involved.