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Sustained-release lipid pre-concentrate of cationic pharmacologically active substance and pharmaceutical composition comprising the same
专利权人:
Chong Kun Dang Pharmaceutical Corp.
发明人:
Yu, Ha Na,Baik, Hye Jung,Yang, Won Kyu,Ko, Jin Young,Jung, Sung Bum,An, Sung Won,Ki, Min Hyo
申请号:
AU2013371094
公开号:
AU2013371094B2
申请日:
2013.12.27
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
Disclosed is a sustained-release lipid pre-concentrate, comprising: a) at least one liquid crystal former; b) at least one neutral phospholipid; c) at least one liquid crystal hardener; and d) at least one anionic anchoring agent, wherein the sustained-release pre-concentrate exists as a lipid liquid phase in the absence of aqueous fluid and forms into a liquid crystal upon exposure to aqueous fluid. The sustained-release lipid pre-concentrate is configured to enhance the sustained release of cationic pharmacologically active substance through ionic interaction between the anionic anchoring agent and the cationic pharmacologically active substance.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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