Yu, Ha Na,Baik, Hye Jung,Yang, Won Kyu,Ko, Jin Young,Jung, Sung Bum,An, Sung Won,Ki, Min Hyo
申请号：
AU2013371094
公开号：
AU2013371094B2
申请日:
2013.12.27
申请国别(地区):
AU
年份:
2016
代理人:
摘要：
Disclosed is a sustained-release lipid pre-concentrate, comprising: a) at least one liquid crystal former； b) at least one neutral phospholipid； c) at least one liquid crystal hardener； and d) at least one anionic anchoring agent, wherein the sustained-release pre-concentrate exists as a lipid liquid phase in the absence of aqueous fluid and forms into a liquid crystal upon exposure to aqueous fluid. The sustained-release lipid pre-concentrate is configured to enhance the sustained release of cationic pharmacologically active substance through ionic interaction between the anionic anchoring agent and the cationic pharmacologically active substance.
