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SUSTAINED-RELEASE LIPID PRE-CONCENTRATE OF CATIONIC PHARMACOLOGICALLY ACTIVE SUBSTANCE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME
专利权人:
CHONG KUN DANG PHARMACEUTICAL CORP.
发明人:
YU, HA NA,BAIK, HYE JUNG,YANG, WON KYU,KO, JIN YOUNG,JUNG, SUNG BUM,AN, SUNG WON,KI, MIN HYO
申请号:
PH12015501183
公开号:
PH12015501183A1
申请日:
2015.05.27
申请国别(地区):
PH
年份:
2015
代理人:
摘要:
Disclosed is a sustained-release lipid pre-concentrate, comprising: a) at least one liquid crystal former b) at least one neutral phospholipid c) at least one liquid crystal hardener and d) at least one anionic anchoring agent, wherein the sustained-release pre-concentrate exists as a lipid liquid phase in the absence of aqueous fluid and forms into a liquid crystal upon exposure to aqueous fluid. The sustained-release lipid pre-concentrate is configured to enhance the sustained release of cationic pharmacologically active substance through ionic interaction between the anionic anchoring agent and the cationic pharmacologically active substance.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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