INHIBITION OF PROTEIN DISULFIDE-ISOMERASE A3

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专利权人:

Romark Laboratories L.C.

发明人:

Jean-Francois Rossignol,Maria Gabriella Santoro

申请号：

US16605978

公开号：

US20200038377A1

申请日:

2018.04.17

申请国别(地区):

US

年份:

2020

代理人:

摘要：

Provided are methods of treating a disease or condition associated with an increased level of expression of a protein disulfide-isomerase A3 (PDIA3) by administering to a subject with an increased level of expression of PDIA3 a PDI A3-inhibiting effective amount of a thiazolide compound, such as nitazoxanide or tizoxanide. Also provided are methods of screening for therapeutic agents based on PDIA3 inhibition.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/